This Best cream for bad diaper rash is effective for treating and preventing diaper rash, with options containing different levels of zinc oxide. With a high concentration of zinc oxide, this cream provides a protective barrier and helps soothe irritated skin. La Petite Creme is certified Organic and safe to use from birth on the most sensitive skins. This Best cream for bad diaper rash multipurpose ointment can be very effective in soothing and healing diaper rash while keeping the skin moisturized.